CorMatrix ECM Technology

Found in all humans and animals, extracellular matrix or ECM is the naturally-occurring bioscaffold that surrounds cells in almost all tissues and organ structures. CorMatrix ECM Technology supports tissue repair and results in remodeled, functional tissue without leading to encapsulation, premature breakdown of the material, calcification, or tissue erosion that can be caused by synthetic materials.

  • CorMatrix ECM Technology

    CorMatrix ECM Technology is a unique extracellular matrix that combines the innate attributes of nature with the precision of science to help the heart heal itself. It is an acellular biomaterial that does not encapsulate when surgically implanted, but is gradually remodeled, leaving behind organized and healthy tissue. The body’s tissue begins remodeling at the surgical site while the ECM maintains the needed tissue support. When implanted, the ECM acts as a scaffold into which the patient’s cells migrate and integrate, stimulating the patient’s natural wound-healing mechanisms. As the patient’s cells become active, they lay down their own collagen, which matures over time to form strong and permanent tissue repair without leaving behind permanent foreign material. Because the ECM contains primarily collagen, the device is gradually replaced as the patient’s tissue gradually turns over in a natural state of self-renewal.

    CorMatrix ECM Technology allows surgeons to restore the native anatomy of cardiovascular tissue in need of repair. Serving as a superior alternative to synthetic or cross-linked materials, the implanted CorMatrix ECM is remodeled over time, leaving the patient with only restored tissue structure instead of scar or injured tissue that would normally be expected when synthetic or cross-linked materials are used.

    CorMatrix ECM products are designed to support the mechanical requirements necessary for site specific repair. Over time, CorMatrix ECM remodels to maintain strength while allowing growth of the patient's own tissue.